The main reasons for this are as follows:

Main causes of reduced blood flow
Atherosclerosis: The main cause is the accumulation of fat (cholesterol) and other substances in the blood vessels, which narrows the inner lining of the arteries. This obstructs blood flow.

Smoking: Smoking damages the walls of the blood vessels and greatly increases the risk of blockages in the arteries. Smoking can worsen the disease in people with PAD.

 

Diabetes: High blood sugar levels damage the blood vessels and slow down blood flow. This is a major reason why wounds on the legs do not heal in diabetics.

High Blood Pressure: High blood pressure damages the arteries to the legs.

High cholesterol: An increase in bad cholesterol (LDL) in the blood causes blockages in the arteries.

Age and lifestyle: Ageing, lack of exercise,